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Off-label sleeping pills; Based on Sleep Disorders Medicine written by Dr. Sudhansu Chokroverty, MD. Several different classes of medications are used to treat insomnia. This list includes both prescription and over-the-counter sedative-hypnotic medications. Non-Benzodiazepine hypnotics (Z-Drugs) Z-drugs are structurally unrelated to each. The best sleeping pill will depend on a person's sleep patterns and needs. People with insomnia and those with jet lag, for instance, may benefit from different medications. Learn about the.

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